Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57078 | 0.92 | KMT2A (0.53) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL1564214 | 0.92 | KMT2A (0.53) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| Ethylene Glycol SCHEMBL3521351 | 0.88 | SLC1A2 (0.47) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL28121172 | 0.84 | KMT2A (0.47) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| Phenylalanine SCHEMBL9392749 | 0.81 | SLC7A5 (0.58) | SLC1A2ALDH1A1PKMSLC7A5 | |
| Proline SCHEMBL16432404 | 0.80 | MEN1 (0.34) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL10609538 | 0.79 | KMT2A (0.53) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL9182487 | 0.77 | KMT2A (0.49) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL18020563 | 0.74 | SLC1A2 (0.45) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B | |
| SCHEMBL542300 | 0.71 | RAB9A (0.41) | KMT2AMEN1SLC1A2CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297315-A2 | COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES | Danisco US Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009149145-A2 | COMPOSITIONS AND METHODS COMPRISING VARIANT MICROBIAL PROTEASES | DANISCO US INC., GENENCOR DIVISION (US) | 2009-12-10 | — | — | WO | disclosed |
| EP-1807108-A2 | METHODS FOR THE TREATMENT AND PREVENTION OF DISEASES OF BIOLOGICAL CONDUITS | Proteon Therapeutics, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006036804-A2 | METHODS FOR THE TREATMENT AND PREVENTION OF DISEASES OF BIOLOGICAL CONDUITS | PROTEON THERAPEUTICS, INC. (US) | 2006-04-06 | — | — | WO | disclosed |