Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | TSHR | P16473 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14213023 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL4860317 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL14213045 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL4857870 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL14213542 | 0.82 | TSHR (0.41) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL14213532 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1TSHRL3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL12019721 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL14213357 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL13035350 | 0.76 | DPP4 (0.44) | ALDH1A1TSHRL3MBTL1ATMSMN1; SMN2 | |
| SCHEMBL13035720 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1TSHRL3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371746-B2 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | CYP4F3, CYP4B1, CYP4X1 | ALDH1A1 248/4885TSHR 84/4885L3MBTL1 203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.