Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28671716 | 0.98 | CASP3 (0.56) | CASP3SENP8SENP7SENP6PRMT5 | |
| Hydrochloric Acid SCHEMBL28572814 | 0.98 | CASP3 (0.56) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL6441482 | 0.92 | CASP3 (0.62) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL15223709 | 0.87 | CASP3 (0.56) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL5443742 | 0.86 | CASP3 (0.77) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL30344399 | 0.86 | CASP3 (0.77) | CASP3SENP8SENP7SENP6PRMT5 | |
| Hydrochloric Acid SCHEMBL29008952 | 0.85 | PRMT5 (0.69) | CASP3SENP8SENP7SENP6PRMT5 | |
| Hydrochloric Acid SCHEMBL29073874 | 0.85 | PRMT5 (0.69) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL28304070 | 0.85 | PRMT5 (0.72) | CASP3SENP8SENP7SENP6PRMT5 | |
| SCHEMBL14213704 | 0.84 | CASP3 (0.54) | CASP3SENP8SENP7SENP6PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |