SCHEMBL1421383

SCHEMBL1421383

O=C(O)C(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19972878 1.00
SCHEMBL19972861 1.00
SCHEMBL9805807 0.75
SCHEMBL11464946 0.75
SCHEMBL27266165 0.74
SCHEMBL27265343 0.74
SCHEMBL27541122 0.73 ALDH1A1 (0.43)
Dibromoacetic Acid SCHEMBL1330871 0.73
SCHEMBL104463 0.73
Dibromoacetic Acid SCHEMBL137199 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107400053-A A kind of green synthesis method of ethyl bromide difluoride 山东飞源新材料有限公司 2017-11-28 CN claimed
EP-2027138-B1 STABLE C-GLYCOSIDE SUGAR AND C-GLYCOCONJUGATE MIMETICS, METHOD FOR PREPARING SAME AND USES THEREOF IN PARTICULAR IN COSMETICS AND DRUGS TFCHEM (FR) 2012-12-05 EP claimed
EP-0223620-B1 PROCESS FOR THE PREPARATION OF BROMO-FLUORO-ACETIC ACID ELF ATOCHEM S.A. (FR) 1989-04-12 EP claimed
US-4806684-A Process for the preparation of bromofluoroacetic acids ATOCHEM (FR) 1989-02-21 US claimed
CN-121698844-A Photoacid generator containing fluorosulfonate and synthesis method thereof 徐州博康化学科技股份有限公司 2026-03-20 CN disclosed
CN-114591223-B Beta-lactamase inhibitor compounds 恩塔西斯治疗有限公司 2025-01-24 CN disclosed
EP-4229056-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS Bristol-Myers Squibb Company (US) 2023-08-23 EP disclosed
CN-114773245-B Preparation method of trifluoromethyl selenoether 南通大学 2023-08-15 CN disclosed
CN-116178242-A Preparation method of diindolylmethane alkaloid and derivative thereof catalyzed by recyclable photocatalyst 中国人民解放军海军军医大学 2023-05-30 CN disclosed
CN-114349690-B Synthesis method of doravirine intermediate 甘肃皓天医药科技有限责任公司 2023-04-25 CN disclosed
CN-115650926-A Azole selenone functional reagent and application thereof 华南农业大学 2023-01-31 CN disclosed
EP-3512851-B1 BETA-LACTAMASE INHIBITOR COMPOUNDS ENTASIS THERAPEUTICS LTD (GB) 2022-07-06 EP disclosed
US-4356313-A [(5,6,9a-substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acid esters and their analogs, the parent acids and their salts MERCK & CO., INC. (US) 1982-10-26 US disclosed
US-4356314-A [5,6,9A-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids, their analogs, esters, salts, and derivatives MERCK & CO., INC. (US) 1982-10-26 US disclosed
US-4337354-A BRAIN AND SPINAL CHORD DAMAGE MERCK & CO., INC. (US) 1982-06-29 US disclosed
US-4317922-A [(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alkanoic and cycloalkanoic acids and their analogs, esters, salts and derivatives MERCK & CO., INC. (US) 1982-03-02 US disclosed
US-4316043-A ANTIEDEMIC AGENTS MERCK & CO., INC. (US) 1982-02-16 US disclosed
EP-0027948-A1 Tetrahydro-fluorene compounds, processes for their preparation and pharmaceutical compositions thereof MERCK & CO. INC. (US) 1981-05-06 EP disclosed
US-4122115-A FROM THE ACETIC ACID AND CHLOROSULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed
US-4122115-A FROM THE ACETIC ACID AND CHLOROSULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US disclosed