SCHEMBL14214847 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	NR3C1	P04150	15/20	0.58

▸	PGR	P06401	3/20	0.51

▸	POLB	P06746	1/20	0.50

▸	AR	P10275	2/20	0.48

▸	MAPT	P10636	1/20	0.47

▸	TSHR	P16473	1/20	0.47

▸	FFAR2	O15552	1/20	0.44

▸	KDM4E	B2RXH2	1/20	0.43

▸	NPC1	O15118	1/20	0.43

▸	LMNA	P02545	1/20	0.43

▸	NFKB1	P19838	1/20	0.43

▸	RAB9A	P51151	1/20	0.43

▸	NFKB2	Q00653	1/20	0.43

▸	RELA	Q04206	1/20	0.43

▸	SMN1; SMN2	Q16637	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2899060	0.90	NR3C1 (0.57)	NR3C1PGRARFFAR2KDM4E
SCHEMBL2899518	0.88	NR3C1 (0.62)	NR3C1PGRARFFAR2
SCHEMBL2901819	0.88	NR3C1 (0.59)	NR3C1PGRAR
SCHEMBL2898787	0.88	NR3C1 (0.59)	NR3C1PGRAR
SCHEMBL2901081	0.87	NR3C1 (0.55)	NR3C1PGRARFFAR2KDM4E
SCHEMBL2893413	0.86	NR3C1 (0.54)	NR3C1PGRARMAPTNPC1
SCHEMBL2893963	0.86	NR3C1 (0.54)	NR3C1PGRPOLBARFFAR2
SCHEMBL2900926	0.86	NR3C1 (0.54)	NR3C1PGRARFFAR2
SCHEMBL2901362	0.86	NR3C1 (0.54)	NR3C1PGRAR
SCHEMBL2898906	0.86	NR3C1 (0.54)	NR3C1PGRARFFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008057862-A2	MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-&kappav;B ACTIVITY AND USE THEREOF	BRISTOL-MYERS SQUIBB COMPANY (US)	2008-05-15	—	—	WO	disclosed