Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.69 |
| ▸ | PGR | P06401 | 4/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2901564 | 1.00 | NR3C1 (0.69) | NR3C1PGRAR | |
| SCHEMBL12592839 | 1.00 | NR3C1 (0.69) | NR3C1PGRAR | |
| SCHEMBL2895630 | 0.93 | NR3C1 (0.62) | NR3C1PGRAR | |
| SCHEMBL2893200 | 0.92 | NR3C1 (0.58) | NR3C1PGRAR | |
| SCHEMBL2901385 | 0.92 | NR3C1 (0.72) | NR3C1PGRAR | |
| SCHEMBL2892206 | 0.91 | NR3C1 (0.59) | NR3C1PGRAR | |
| SCHEMBL2892048 | 0.91 | NR3C1 (0.59) | NR3C1PGRAR | |
| SCHEMBL2901471 | 0.91 | NR3C1 (0.70) | NR3C1PGRAR | |
| SCHEMBL2896318 | 0.91 | NR3C1 (0.59) | NR3C1PGRAR | |
| SCHEMBL2893720 | 0.90 | NR3C1 (0.60) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057862-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |