Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895550 | 0.80 | ACP1 (0.60) | ACP1KMT2ASENP7CASRGAA | |
| SCHEMBL27004443 | 0.69 | KMT2A (0.60) | ACP1KMT2ASENP7GAAMAPK1 | |
| SCHEMBL2901060 | 0.69 | ACP1 (0.61) | ACP1KMT2AMAPK1TSHRNPSR1 | |
| SCHEMBL30754208 | 0.67 | DYRK1A (0.71) | ACP1KMT2ASENP7GAAMAPK1 | |
| SCHEMBL2899015 | 0.66 | ACP1 (0.63) | ACP1KMT2ACASRGAAMAPK1 | |
| SCHEMBL18289894 | 0.66 | ACP1 (1.00) | ACP1KMT2ASENP7GAAMAPK1 | |
| SCHEMBL15756371 | 0.64 | MAPK1 (0.62) | ACP1KMT2ASENP7GAAMAPK1 | |
| SCHEMBL2898880 | 0.64 | NR3C1 (0.53) | ACP1 | |
| SCHEMBL24071457 | 0.64 | KMT2A (0.55) | ACP1KMT2ASENP7GAAMAPK1 | |
| SCHEMBL2901429 | 0.64 | CSNK1D (0.66) | ACP1KMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057862-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |