Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.73 |
| ▸ | PGR | P06401 | 4/20 | 0.68 |
| ▸ | AR | P10275 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899087 | 0.89 | NR3C1 (0.77) | NR3C1PGRAR | |
| SCHEMBL12592875 | 0.89 | NR3C1 (0.77) | NR3C1PGRAR | |
| SCHEMBL2901550 | 0.89 | NR3C1 (0.77) | NR3C1PGRAR | |
| SCHEMBL12592898 | 0.87 | NR3C1 (0.71) | NR3C1PGRAR | |
| SCHEMBL2901234 | 0.86 | NR3C1 (0.78) | NR3C1PGRAR | |
| SCHEMBL12592842 | 0.85 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL12592843 | 0.85 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL2893737 | 0.85 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL2896226 | 0.84 | NR3C1 (1.00) | NR3C1PGRAR | |
| SCHEMBL2903919 | 0.84 | NR3C1 (0.82) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057862-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |