Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2746762 | 0.87 | EPHX2 (0.49) | ALDH1A1GAAEPHX2EPHX1LMNA | |
| SCHEMBL5537204 | 0.84 | EPHX2 (0.47) | ALDH1A1GAAEPHX2EPHX1LMNA | |
| SCHEMBL19176862 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAEPHX2EPHX1LMNA | |
| SCHEMBL19169605 | 0.83 | TP53 (0.46) | ALDH1A1GAAEPHX2EPHX1LMNA | |
| SCHEMBL21638019 | 0.82 | ALDH1A1 (0.44) | ALDH1A1GAAEPHX2EPHX1LMNA | |
| SCHEMBL5537247 | 0.82 | EPHX2 (0.57) | ALDH1A1GAAEPHX2LMNANPSR1 | |
| SCHEMBL4919816 | 0.82 | EPHX2 (0.65) | ALDH1A1EPHX2EPHX1LMNATP53 | |
| SCHEMBL10266067 | 0.81 | ALDH1A1 (0.56) | ALDH1A1GAALMNAPOLBCA12 | |
| SCHEMBL2937346 | 0.80 | TP53 (0.58) | ALDH1A1EPHX2EPHX1LMNATP53 | |
| SCHEMBL14383590 | 0.80 | EPHX2 (0.55) | ALDH1A1EPHX2EPHX1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9993554-B2 | Use of P13K Inhibitors for the Treatment of Obesity, Steatosis and ageing | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2018-06-12 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | SHIONOGI & CO. LTD. (JP) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103139-A1 | 3-Carbamoyl-2-Pyridone Derivative | CNR1, CNR2, HRH4 | ALDH1A1 4132/4885GAA 4580/4885EPHX2 1521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.