Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009687 | 1.00 | IDH1 (0.77) | IDH1HSD11B1 | |
| SCHEMBL3398228 | 0.98 | IDH1 (0.77) | IDH1HSD11B1 | |
| SCHEMBL2009565 | 0.92 | IDH1 (0.87) | IDH1HSD11B1 | |
| SCHEMBL3244150 | 0.92 | IDH1 (0.87) | IDH1HSD11B1 | |
| SCHEMBL14215867 | 0.92 | IDH1 (0.87) | IDH1HSD11B1 | |
| SCHEMBL1975562 | 0.92 | IDH1 (0.87) | IDH1HSD11B1 | |
| SCHEMBL1992164 | 0.89 | HSD11B1 (0.73) | IDH1HSD11B1 | |
| SCHEMBL1968317 | 0.85 | IDH1 (0.85) | IDH1HSD11B1 | |
| SCHEMBL3398299 | 0.85 | IDH1 (0.59) | IDH1HSD11B1 | |
| Azd-4017 SCHEMBL1967884 | 0.85 | HSD11B1 (1.00) | IDH1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008053194-A2 | PYRIDINE CARBOXAMIDES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-08 | — | — | WO | disclosed |