Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.85 |
| ▸ | HTT | P42858 | 1/20 | 0.85 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.72 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.52 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.52 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trypan Blue Free Acid SCHEMBL29415031 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| Trypan Blue Free Acid SCHEMBL29376676 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| Trypan Blue Free Acid SCHEMBL29355441 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| Trypan Blue Free Acid SCHEMBL12234090 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| Trypan Blue Free Acid SCHEMBL15497820 | 0.92 | MEN1 (1.00) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| SCHEMBL13243797 | 0.90 | MEN1 (0.94) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| SCHEMBL24438814 | 0.86 | MEN1 (0.87) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| SCHEMBL14188865 | 0.86 | MEN1 (0.63) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| SCHEMBL18784959 | 0.85 | MEN1 (0.85) | MEN1KMT2AHTTPHLPP2ENPP2 | |
| SCHEMBL21105389 | 0.85 | MEN1 (0.85) | MEN1KMT2AHTTPHLPP2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368099-B2 | containing imaging unit with unpaired electron-carrying atom (Gd), capable of amplifying MRI signals and detection unit, capable of selectively recognizing exfoliated vascular endothelial sites (azo dye); directly detecting injured or inflamed vascular sites; low-cost, simple preparation | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |