Trypan Blue Free Acid

Trypan Blue Free Acid

SCHEMBL29376676

Cc1cc(-c2ccc(/N=N/c3c(S(=O)(=O)O)cc4cc(S(=O)(=O)O)cc(N)c4c3O)c(C)c2)ccc1/N=N/c1c(S(=O)(=O)O)cc2cc(S(=O)(=O)O)cc(N)c2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ HTT P42858 1/20 1.00
▸ PHLPP2 Q6ZVD8 2/20 0.82
▸ ENPP2 Q13822 9/20 0.76
▸ PTPN1 P18031 2/20 0.74
▸ USP2 O75604 1/20 0.74
▸ ATM Q13315 1/20 0.74
▸ L3MBTL1 Q9Y468 1/20 0.74
▸ CYP1A2 P05177 2/20 0.60
▸ SUMO2 P61956 1/20 0.59
▸ SUMO1 P63165 1/20 0.59
▸ SENP7 Q9BQF6 1/20 0.59
▸ SENP3 Q9H4L4 1/20 0.59
▸ SENP2 Q9HC62 1/20 0.59
▸ SENP1 Q9P0U3 1/20 0.59
▸ PRMT1 Q99873 1/20 0.56
▸ ALDH1A1 P00352 2/20 0.53
▸ CYP2C9 P11712 2/20 0.53
▸ MAPK1 P28482 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trypan Blue Free Acid SCHEMBL15497820 1.00 MEN1 (1.00) MEN1KMT2AHTTPHLPP2ENPP2
Trypan Blue Free Acid SCHEMBL12234090 1.00 MEN1 (1.00) MEN1KMT2AHTTPHLPP2ENPP2
Trypan Blue Free Acid SCHEMBL29355441 1.00 MEN1 (1.00) MEN1KMT2AHTTPHLPP2ENPP2
Trypan Blue Free Acid SCHEMBL29415031 1.00 MEN1 (1.00) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL13243797 0.97 MEN1 (0.94) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL24438814 0.93 MEN1 (0.87) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL18784959 0.92 MEN1 (0.85) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL21105389 0.92 MEN1 (0.85) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL20128454 0.92 MEN1 (0.85) MEN1KMT2AHTTPHLPP2ENPP2
SCHEMBL14215680 0.92 MEN1 (0.85) MEN1KMT2AHTTPHLPP2ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115074325-A Herceptin combined 4-1BBL in-vitro amplification NK method 广州希灵生物科技有限公司 2022-09-20 — — CN claimed
EP-4739346-A1 COMBINATION THERAPIES FOR THE TREATMENT OF CANCER D3 Bio(Wuxi) Co., Ltd. (CN) 2026-05-13 — — EP disclosed
US-20260103679-A1 COMPOSITIONS COMPRISING REGULATORY T CELLS AND METHODS OF USING THE SAME CELLENKOS INC (IS) 2026-04-16 — — US disclosed
US-12578333-B2 Aerosol biosensors and related aspects for pathogen detection THE JOHNS HOPKINS UNIVERSITY (US) 2026-03-17 — — US disclosed
US-20260053853-A1 ENGINEERED T CELL RECEPTOR CONSTRUCTS FOR CANCER THERAPY HADASIT MED RES SERVICE (IL) 2026-02-26 — — US disclosed
US-20260049290-A1 HUMAN SPINAL CORD INJURY ORGANOIDS UNIV NORTHWESTERN (US) 2026-02-19 — — US disclosed
US-20260027201-A1 Methods of Treating Glioblastoma EMORY UNIVERSITY (US) 2026-01-29 — — US disclosed
US-20260021181-A1 CHIMERIC COSTIMULATORY RECEPTORS, CHEMOKINE RECEPTORS, AND THE USE OF SAME IN CELLULAR IMMUNOTHERAPIES IOVANCE BIOTHERAPEUTICS INC (US) 2026-01-22 — — US disclosed
US-20250333698-A1 SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER UNIV GEORGIA STATE RES FOUND (US) 2025-10-30 — — US disclosed
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto GEORGE MASON RES FOUNDATION INC (US) 2025-10-30 — — US disclosed
CN-114430681-A Treatment of EGFR mutation-related cancers with combinations of EGFR and CDK4/6 inhibitors 贝达医药公司 2022-05-03 — — CN disclosed
WO-2022081452-A1 NOVEL NR1 ES-DERIVED NEURAL STEM CELLS HAVING A NORMAL KARYOTYPE AND USES THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-04-21 — — WO disclosed
EP-3980041-A1 BIOTHERAPY FOR VIRAL INFECTIONS USING BIOPOLYMER BASED MICRO/NANOGELS THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2022-04-13 — — EP disclosed
EP-3976183-A1 ANTI-TNF ANTIBODIES, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF ACTIVE ANKYLOSING SPONDYLITIS Janssen Biotech, Inc. (US) 2022-04-06 — — EP disclosed
US-20220073881-A1 COMPOSITIONS AND METHODS FOR IMPLANTATION OF PROCESSED ADIPOSE TISSUE AND PROCESSED ADIPOSE TISSUE PRODUCTS THE JOHNS HOPKINS UNIVERSITY 2022-03-10 — — US disclosed
EP-3963050-A1 PREPARATION OF HUMAN ALLOGENEIC LIVER-DERIVED PROGENITOR CELLS PROMETHERA THERAPEUTICS SA (BE) 2022-03-09 — — EP disclosed
EP-3963049-A1 PREPARATION OF HUMAN ALLOGENEIC LIVER-DERIVED PROGENITOR CELLS PROMETHERA THERAPEUTICS SA (BE) 2022-03-09 — — EP disclosed
EP-3947645-A1 ADULT LIVER PROGENITOR CELLS FOR TREATING NON-ALCOHOLIC FATTY LIVER DISEASE PROMETHERA THERAPEUTICS SA (BE) 2022-02-09 — — EP disclosed
EP-3947644-A1 ADULT LIVER PROGENITOR CELLS FOR TREATING ACUTE-ON-CHRONIC LIVER FAILURE PROMETHERA THERAPEUTICS SA (BE) 2022-02-09 — — EP disclosed
WO-2022026495-A1 ANTIMICROBIAL SILK NANOPARTICLES AND METHODS FOR MAKING AND USING THE SAME UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12578333-B2 Aerosol biosensors and related aspects for pathogen detection ACE2, ACE, TMPRSS2 MEN1 4732/4885KMT2A 4587/4885HTT 4424/4885
US-20260103679-A1 COMPOSITIONS COMPRISING REGULATORY T CELLS AND METHODS OF USING THE SAME CD4, CCR9, CD2 MEN1 4340/4885KMT2A 3334/4885HTT 3875/4885
US-20250333472-A1 Binding Domain Mapping and Compounds, Compositions, Complexes, Methods, and Kits Related Thereto SNRPE, SSBP1, RPA1 MEN1 3891/4885KMT2A 4392/4885HTT 2693/4885
US-20260049290-A1 HUMAN SPINAL CORD INJURY ORGANOIDS NES, SMN1; SMN2, NCDN MEN1 3550/4885KMT2A 403/4885HTT 274/4885
US-20260021181-A1 CHIMERIC COSTIMULATORY RECEPTORS, CHEMOKINE RECEPTORS, AND THE USE OF SAME IN CELLULAR IMMUNOTHERAPIES CCR3, IL2, IL2RA MEN1 4656/4885KMT2A 766/4885HTT 4245/4885
US-20260053853-A1 ENGINEERED T CELL RECEPTOR CONSTRUCTS FOR CANCER THERAPY TAP1, MICA, CD74 MEN1 3523/4885KMT2A 2719/4885HTT 2582/4885
US-20260027201-A1 Methods of Treating Glioblastoma ICOS, IL2, CD4 MEN1 822/4885KMT2A 1006/4885HTT 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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