SCHEMBL14215822

SCHEMBL14215822

O=C(CF)CC(=O)C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLOD2 O00469 3/20 0.39
PLOD3 O60568 2/20 0.38
PLOD1 Q02809 2/20 0.38
FAAH O00519 8/20 0.36
CES1 P23141 7/20 0.34
CES2 O00748 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA2 P00918 1/20 0.33
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720470 0.85 PLOD2 (0.43) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL183178 0.78 PLOD2 (0.46) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL1948056 0.76 TDP1 (0.45) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL1034297 0.76 KMT2A (0.31) KMT2A
SCHEMBL4976795 0.76 PLOD2 (0.38) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL31303653 0.76 PLOD2 (0.38) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL9283764 0.76 PLOD2 (0.44) PLOD2PLOD3PLOD1FAAHCES1
SCHEMBL9326020 0.76 PLOD2 (0.44) PLOD2PLOD3PLOD1FAAHCES1
Water SCHEMBL7191917 0.76 PLOD2 (0.44) PLOD2PLOD3PLOD1FAAHCES1
Water SCHEMBL7197275 0.76 PLOD2 (0.44) PLOD2PLOD3PLOD1FAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11021418-B2 Method of olefin oligomerization SK INNOVATION CO., LTD. (KR) 2021-06-01 US disclosed
US-20200262767-A1 Method of Olefin Oligomerization SK INNOVATION CO, LTD. (KR) 2020-08-20 US disclosed
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262767-A1 Method of Olefin Oligomerization OXER1, OSR1, OXSR1 PLOD2 3092/4885PLOD3 4827/4885PLOD1 3116/4885
US-11021418-B2 Method of olefin oligomerization OXER1, OSR1, OXSR1 PLOD2 3092/4885PLOD3 4827/4885PLOD1 3116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.