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PLOD2

Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 · O00469 · PLOD2 on Sugi Atlas →

8,660 patent compounds predicted against PLOD2, 6,157 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1924749 SCHEMBL1924749 1.00 5/20
SCHEMBL1925385 SCHEMBL1925385 1.00 5/20
SCHEMBL523476 SCHEMBL523476 0.69 5/20
SCHEMBL1682774 SCHEMBL1682774 0.50 5/20
SCHEMBL1682776 SCHEMBL1682776 0.47 5/20
SCHEMBL711849 SCHEMBL711849 1.00 3/20
SCHEMBL200805 SCHEMBL200805 0.73 3/20
SCHEMBL1095373 SCHEMBL1095373 0.72 3/20
SCHEMBL313164 SCHEMBL313164 0.70 3/20
SCHEMBL583455 SCHEMBL583455 0.70 3/20
SCHEMBL584065 SCHEMBL584065 0.70 3/20
SCHEMBL1593867 SCHEMBL1593867 0.70 3/20
SCHEMBL340946 SCHEMBL340946 0.66 3/20
SCHEMBL1925141 SCHEMBL1925141 0.66 3/20
SCHEMBL1924322 SCHEMBL1924322 0.64 3/20
SCHEMBL1919299 SCHEMBL1919299 0.60 3/20
SCHEMBL1924261 SCHEMBL1924261 0.60 3/20
SCHEMBL1924352 SCHEMBL1924352 0.60 3/20
SCHEMBL1924889 SCHEMBL1924889 0.60 3/20
SCHEMBL1349410 SCHEMBL1349410 0.59 3/20

Clinical trials — most relevant to PLOD2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers PHASE2NOT_YET_RECRUITING
Prolonged Release Pirfenidone Versus Placebo in Compensated Cirrhosis. PHASE2COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes PHASE2UNKNOWN
Systemic Markers of Collagen Metabolism and Vitamin C in Smokers and Non-Smokers With Pelvic Organ Prolapse nanCOMPLETED
Mitochondrial Function of Immune Cells in Sepsis nanCOMPLETED
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD nanUNKNOWN
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions nanRECRUITING
The Relation Between Serum Ascorbic Acid Concentration and Preterm Premature Rupture of Membranes nanUNKNOWN
Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages nanCOMPLETED
Clubfoot DNA Repository nanCOMPLETED
ProGo Menopause Wellbeing Study nanNOT_YET_RECRUITING
Collagenase Chemonucleolysis vs Percutaneous Endoscopic Lumbar Discectomy (PELD) for Lumbar Disc Herniation nanUNKNOWN
Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia nanCOMPLETED
T1 Mapping of Diffuse Myocardial Fibrosis in Congenital Heart Disease nanCOMPLETED
The LD Lync Study - Natural History Study of Lipodystrophy Syndromes nanRECRUITING
Pilot Study of Non-Invasive Assessment of Hepatic And Myocardial Iron Through T2* Magnet Resonance Imaging (MRI) In Patients With Iron Overload nanCOMPLETED
Whole Genome Analysis for the Detection of Key Genes in the Polycystic Ovary Syndrome nanUNKNOWN
Remote Ischemic Postconditioning Increases HIF-1α Plasma Levels and Improves Cardiac Markers After Cardiac Surgery nanCOMPLETED
The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients nanCOMPLETED
Genetic Analysis of Keloids nanRECRUITING
Replacement of Vitamin D in Patients With Active Tuberculosis nanCOMPLETED
Genetic Determinants of Congenital Heart Disease Outcomes nanCOMPLETED
Education to Decrease in Sodium Intake Evaluated With 24 Hour Urinary Sodium Excretion (RCT) nanCOMPLETED
Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia nanCOMPLETED
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract nanUNKNOWN
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) nanUNKNOWN
A Feasibility Study: Assessing Photobiomodulation in Myalgic Encephalomyelitis nanUNKNOWN
Biomarkers in the Diagnosis and Prognosis of NAFLD nanRECRUITING
Sodium Transport: Genetics and Hypertension nanCOMPLETED
Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PLOD2 binder may also engage these)

ProteinNameSimilarity
Q811A3 — 1.000 Q811A3 →
Q9R0B9 — 0.998 Q9R0B9 →
O77588 — 0.992 O77588 →
Q9R0E2 — 0.992 Q9R0E2 →
Q5R9N3 — 0.990 Q5R9N3 →
PLOD1 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 0.986 landscape →
P24802 — 0.985 P24802 →
Q63321 — 0.984 Q63321 →
Q20679 — 0.982 Q20679 →
Q9VTH0 — 0.981 Q9VTH0 →
Q17FB8 — 0.980 Q17FB8 →
Q6NVG7 — 0.977 Q6NVG7 →
E9KID3 — 0.976 E9KID3 →
GALNT13 Polypeptide N-acetylgalactosaminyltransferase 13 0.976 landscape →
P87172 — 0.976 P87172 →
Q8CF93 — 0.975 Q8CF93 →
Q8IYK4 — 0.975 Q8IYK4 →
Q9FF10 — 0.975 Q9FF10 →
P4HA1 Prolyl 4-hydroxylase subunit alpha-1 0.975 landscape →
Q6UE39 — 0.975 Q6UE39 →
Q1RMU3 — 0.974 Q1RMU3 →
Q7Q021 — 0.974 Q7Q021 →
Q29121 — 0.974 Q29121 →
Q494Q2 — 0.974 Q494Q2 →
Q10576 — 0.974 Q10576 →
Q60HG2 — 0.974 Q60HG2 →
Q68G38 — 0.973 Q68G38 →
GALNT1 Polypeptide N-acetylgalactosaminyltransferase 1 0.973 landscape →
Q6DE40 — 0.973 Q6DE40 →
Q07537 — 0.973 Q07537 →