Deoxylactucin

Deoxylactucin

SCHEMBL14215979

C=C1C(=O)O[C@@H]2[C@H]3C(CO)=CC(=O)C3=C(C)CC[C@@H]12

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.72
PKM P14618 6/20 0.45
NLRP3 Q96P20 2/20 0.45
ALDH1A1 P00352 5/20 0.39
CYP1A2 P05177 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
LMNA P02545 3/20 0.38
TP53 P04637 3/20 0.38
CYP3A4 P08684 3/20 0.38
NFKB1 P19838 2/20 0.38
STAT6 P42226 2/20 0.38
MAPT P10636 2/20 0.38
CASP1 P29466 1/20 0.38
PTGS2 P35354 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dehydroleucodin SCHEMBL4998391 0.84 CYP19A1 (1.00) CYP19A1PKMNLRP3ALDH1A1CYP1A2
SCHEMBL29974110 0.83 CYP19A1 (0.61) CYP19A1PKMNLRP3ALDH1A1CYP1A2
SCHEMBL16028497 0.79 CYP19A1 (0.53) CYP19A1PKMNLRP3ALDH1A1
Lactucin SCHEMBL14215975 0.78 CYP19A1 (0.43) CYP19A1PKMALDH1A1CYP1A2LMNA
Lactucin SCHEMBL11891057 0.78 CYP19A1 (0.43) CYP19A1PKMALDH1A1CYP1A2LMNA
Lactucin SCHEMBL11030649 0.78 CYP19A1 (0.43) CYP19A1PKMALDH1A1CYP1A2LMNA
SCHEMBL14215976 0.75 CYP1A2 (0.71) CYP19A1ALDH1A1CYP1A2MEN1KMT2A
SCHEMBL14533824 0.73 CYP1A2 (0.52) CYP19A1ALDH1A1CYP1A2MEN1KMT2A
SCHEMBL29518021 0.70 CYP19A1 (0.50) CYP19A1PKMNLRP3ALDH1A1CYP1A2
SCHEMBL30471322 0.69 CYP19A1 (0.61) CYP19A1PKMNLRP3ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2986146-B1 VEGETABLE BASED PRODUCTS AND USES THEREOF WHOLEFIBER HOLDING B V (NL) 2026-02-11 EP disclosed
US-12433309-B2 Vegetable based products and uses thereof FSK CONSULTING, LLC (US) 2025-10-07 US disclosed
US-20230284663-A1 VEGETABLE BASED PRODUCTS AND USES THEREOF FSK CONSULTING, LLC 2023-09-14 US disclosed
US-11350654-B2 Vegetable based products and uses thereof FSK CONSULTING, LLC (US) 2022-06-07 US disclosed
US-20080124772-A1 Plant enzymes for bioconversion PLANT RESEARCH INTERNATIONAL B.V. 2008-05-29 US disclosed
US-7214507-B2 Plant enzymes for bioconversion PLANT RESEARCH INTERNATIONAL B.V. (NL) 2007-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124772-A1 Plant enzymes for bioconversion STS, SQLE, CYP51A1 CYP19A1 143/4885PKM 1288/4885NLRP3 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.