Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactucin SCHEMBL11891057 | 1.00 | CYP19A1 (0.43) | CYP19A1MAPK1LMNACYP1A2NPC1 | |
| Lactucin SCHEMBL11030649 | 1.00 | CYP19A1 (0.43) | CYP19A1MAPK1LMNACYP1A2NPC1 | |
| SCHEMBL31006724 | 0.85 | CYP19A1 (0.58) | CYP19A1MAPK1LMNACYP1A2NPC1 | |
| SCHEMBL16180363 | 0.81 | NPC1 (0.43) | CYP19A1NPC1MAPTHTTRAB9A | |
| SCHEMBL16029264 | 0.80 | ACHE (0.38) | CYP19A1MAPK1PTPN1 | |
| Deoxylactucin SCHEMBL14215979 | 0.78 | CYP19A1 (0.72) | CYP19A1MAPK1LMNACYP1A2NPC1 | |
| SCHEMBL14215974 | 0.75 | CYP1A2 (0.72) | MAPK1LMNACYP1A2ALDH1A1 | |
| SCHEMBL8898751 | 0.75 | CYP1A2 (0.72) | MAPK1LMNACYP1A2ALDH1A1 | |
| SCHEMBL14533823 | 0.74 | CYP1A2 (0.54) | MAPK1LMNACYP1A2PTPN1ALDH1A1 | |
| SCHEMBL30252306 | 0.68 | CYP19A1 (0.52) | CYP19A1MAPK1LMNACYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124772-A1 | Plant enzymes for bioconversion | PLANT RESEARCH INTERNATIONAL B.V. | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124772-A1 | Plant enzymes for bioconversion | STS, SQLE, CYP51A1 | CYP19A1 143/4885MAPK1 3955/4885LMNA 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.