SCHEMBL1421736

SCHEMBL1421736

CC(C)C[C@H](N)C(=O)OC(=O)[C@@H](N)[C@@H](C)O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.47
SLC1A3 P43003 3/20 0.37
SLC1A2 P43004 3/20 0.37
ANPEP P15144 6/20 0.36
RNPEP Q9H4A4 2/20 0.36
DNPEP Q9ULA0 2/20 0.36
LAP3 P28838 5/20 0.34
AAK1 Q2M2I8 1/20 0.33
ERAP1 Q9NZ08 1/20 0.32
SLC1A1 P43005 2/20 0.32
CIT O14578 1/20 0.31
LARS1 Q9P2J5 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100153 0.88 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL995721 0.88 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL11768678 0.86 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL244214 0.86 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7863894 0.83 PDCD1LG2 (0.31)
Threonine SCHEMBL3495953 0.82 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL14485413 0.82 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7676359 0.82 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL1585736 0.82 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7361839 0.82 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2523662-A1 \"COMPOSITIONS COMPRISING AMINO ACIDS FOR PREVENTION AND/OR TREATMENT OF RENAL DISORDERS\ Professional Dietetics S.r.l. (IT) 2012-11-21 EP claimed
WO-2011086507-A1 \"COMPOSITIONS COMPRISING AMINO ACIDS FOR PREVENTION AND/OR TREATMENT OF RENAL DISORDERS\ PROFESSIONAL DIETETICS S.R.L. (IT) 2011-07-21 WO claimed
EP-2296642-A1 COMPOSITIONS COMPRISING AMINO ACIDS, WITH PRO-ANGIOGENIC ACTIVITY Professional Dietetics S.r.l. (IT) 2011-03-23 EP claimed
WO-2009147637-A1 COMPOSITIONS COMPRISING AMINO ACIDS, WITH PRO-ANGIOGENIC ACTIVITY PROFESSIONAL DIETETICS S.R.L. (IT) 2009-12-10 WO claimed
US-20160177419-A1 METHOD FOR SEPARATION OF RARE EARTH ION KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2016-06-23 US disclosed
US-20150265572-A1 INJECTABLE CANCER COMPOSITIONS GENSPERA, INC. (US) 2015-09-24 US disclosed
EP-2908838-A2 INJECTABLE CANCER COMPOSITIONS Genspera, Inc. (US) 2015-08-26 EP disclosed
WO-2014062587-A2 INJECTABLE CANCER COMPOSITIONS GENSPERA, INC. (US) 2014-04-24 WO disclosed