SCHEMBL7863894

SCHEMBL7863894

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nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1LG2 Q9BQ51 1/20 0.31
CD274 Q9NZQ7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valine SCHEMBL3443442 0.89 SLC7A5 (0.44) PDCD1LG2CD274
SCHEMBL8712673 0.87 SLC7A5 (0.37)
SCHEMBL995487 0.84 ALOX15 (0.36)
SCHEMBL11061010 0.84 ALOX15 (0.36)
SCHEMBL27906557 0.84 ALOX15 (0.36)
Threonine SCHEMBL1965719 0.83 DPP8 (0.31) PDCD1LG2CD274
SCHEMBL8002645 0.83
SCHEMBL8002637 0.83
SCHEMBL1421736 0.83 SLC7A5 (0.47)
SCHEMBL8679062 0.82 CHRNB2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018150196-A1 CELL PENETRATING PEPTIDES MODIFIED BY GLYCOSYLATION OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2018-08-23 WO claimed
US-4826680-A AUTOIMMUNE DISEASES DR. KURT MULLI NACHF. GMBH & CO. KG (DE) 1989-05-02 US claimed
US-11001824-B1 Carbohydrate-binding protein UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2021-05-11 US disclosed
EP-3737420-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2020-11-18 EP disclosed
EP-3132031-B1 CARBOHYDRATE-BINDING PROTEIN UNIV GEORGIA (US) 2020-10-21 EP disclosed
US-10358637-B2 Carbohydrate-binding protein UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2019-07-23 US disclosed
WO-2019136487-A2 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2019-07-11 WO disclosed
US-20170191049-A1 CARBOHYDRATE-BINDING PROTEIN UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2017-07-06 US disclosed
EP-3132031-A1 CARBOHYDRATE-BINDING PROTEIN The University Of Georgia Research Foundation, Inc (US) 2017-02-22 EP disclosed
WO-2015161201-A1 CARBOHYDRATE-BINDING PROTEIN UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2015-10-22 WO disclosed
US-6235500-B1 BLOOD PROTEIN; FOR USE IN AMPLIFYING OXYGENATION OF ISOLATED ORGAN OR TISSUE THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2001-05-22 US disclosed
EP-0960130-A4 OXYGEN-BINDING HEME PROTEINS INCORPORATING CIRCULARLY-PERMUTED GLOBINS TRUSTEES FOR THE BOARD OF (US) 2001-01-31 EP disclosed
EP-0960130-A1 OXYGEN-BINDING HEME PROTEINS INCORPORATING CIRCULARLY-PERMUTED GLOBINS The Board of Trustees for the University of Illinois (US) 1999-12-01 EP disclosed
US-5770560-A TREATING REDUCED HEMOGLOBIN OXYGEN AFFINITY IN MAMMALS Fischer, James J. (US) 1998-06-23 US disclosed
WO-1998013386-A1 OXYGEN-BINDING HEME PROTEINS INCORPORATING CIRCULARLY-PERMUTED GLOBINS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1998-04-02 WO disclosed
US-5428007-A Increasing oxygenation in hypoxic cells of normal and tumor tissue YALE UNIVERSITY (US) 1995-06-27 US disclosed
US-5173426-A Pure polynucleotide; for increasing tissue oxygenation in patients YALE UNIVERSITY (US) 1992-12-22 US disclosed
EP-0407045-A1 Safe sodium percarbonate composition TOKAI DENKA KOGYO KABUSHIKI KAISHA (JP) 1991-01-09 EP disclosed