Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.70 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492868 | 1.00 | OXTR (0.70) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5041532 | 0.92 | OXTR (0.68) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5482133 | 0.92 | OXTR (0.68) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5482929 | 0.88 | OXTR (0.64) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5482924 | 0.88 | OXTR (0.64) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL24313533 | 0.88 | AVPR1A (0.73) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL14492869 | 0.88 | AVPR1A (0.73) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5041594 | 0.88 | AVPR1A (0.73) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL5041466 | 0.88 | AVPR1A (0.73) | OXTRAVPR1AMMP1MMP3MMP7 | |
| SCHEMBL29642177 | 0.88 | AVPR1A (0.73) | OXTRAVPR1AMMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390347-B1 | PYRROLIDINE ESTER DERIVATIVES WITH OXYTOCIN MODULATING ACTIVITY | SERONO LAB (CH) | 2008-05-07 | — | — | EP | disclosed |
| US-7189754-B2 | Pyrrolidine ester derivatives with oxytocin modulating activity | APPLIED RESEARCH SYSTEMS ARS HOLDING NV (AN) | 2007-03-13 | — | — | US | disclosed |