Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14217937 | 1.00 | PARG (0.36) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL14217955 | 1.00 | PARG (0.36) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL12579055 | 0.87 | SCARB1 (0.40) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL2021312 | 0.87 | SCARB1 (0.40) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL2027138 | 0.87 | SCARB1 (0.40) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL2025539 | 0.87 | SCARB1 (0.40) | PARGACHECA1CA2GRIA2 | |
| SCHEMBL14218082 | 0.87 | PARG (0.34) | PARGACHEGRIA2PTGDR2TBXA2R | |
| SCHEMBL14218081 | 0.86 | PARG (0.38) | PARGPTGDR2CYP2C9 | |
| SCHEMBL16493964 | 0.85 | SRC (0.37) | PARGACHECA1CA2BCHE | |
| SCHEMBL16493965 | 0.85 | SRC (0.37) | PARGACHECA1CA2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |