Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | CCKAR | P32238 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12579060 | 0.87 | HRH1 (0.34) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL2027379 | 0.87 | HRH1 (0.34) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL2024950 | 0.87 | HRH1 (0.34) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL2023272 | 0.87 | HRH1 (0.34) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL14217956 | 0.87 | PARG (0.36) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL14217937 | 0.87 | PARG (0.36) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL14217955 | 0.87 | PARG (0.36) | PARGPTGDR2TBXA2RPTGDRABCB11 | |
| SCHEMBL14218083 | 0.86 | PARG (0.36) | PARGPTGDR2TBXA2RPTGDR | |
| SCHEMBL14217996 | 0.80 | PTGDR2 (0.34) | PARGPTGDR2BCHEACHE | |
| SCHEMBL14218045 | 0.79 | SIGMAR1 (0.35) | PARGPTGDR2BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063867-A2 | TETRAHYDROCYCLOPENTA[B] INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-05-29 | — | — | WO | disclosed |