Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPTLC1 | O15269 | 2/20 | 0.61 |
| ▸ | SPTLC2 | O15270 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | F7 | P08709 | 3/20 | 0.32 |
| ▸ | F3 | P13726 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618543 | 0.83 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHEPHX2 | |
| SCHEMBL6748282 | 0.81 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHCYP3A4 | |
| SCHEMBL6802874 | 0.81 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHSLC6A5EPHX2 | |
| SCHEMBL10082711 | 0.81 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHSLC6A5ASAH2 | |
| SCHEMBL6748227 | 0.81 | SPTLC1 (0.64) | SPTLC1SPTLC2FAAHSLC6A5EPHX2 | |
| SCHEMBL6804868 | 0.81 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAH | |
| SCHEMBL6805680 | 0.81 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHSLC6A5EPHX2 | |
| SCHEMBL14190669 | 0.81 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHSLC6A5EPHX2 | |
| SCHEMBL14190672 | 0.81 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAH | |
| SCHEMBL14190616 | 0.81 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHSLC6A5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378446-B2 | Compound having anti-HCV activity and process for producing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-27 | — | — | US | disclosed |