Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | PRNP | P04156 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979632 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL11932386 | 0.85 | ALDH1A1 (0.68) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL5135579 | 0.85 | ALDH1A1 (0.70) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL4383577 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL5060064 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL17940608 | 0.82 | ALDH1A1 (0.73) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL24158064 | 0.82 | KMT2A (0.72) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL1374171 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KDM4EHSD17B10MAPTLMNA | |
| SCHEMBL14218134 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL1375101 | 0.79 | KDM4E (0.59) | ALDH1A1KDM4EHSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113968-A1 | Substituted piperazines and diazepanes | NOVO NORDISK A/S (DK) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113968-A1 | Substituted piperazines and diazepanes | HRH3, HRH4, HRH1 | ALDH1A1 1907/4885KDM4E 1567/4885HSD17B10 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.