⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284753 | 0.76 | — | — | |
| SCHEMBL19284989 | 0.76 | — | — | |
| SCHEMBL19285034 | 0.76 | — | — | |
| SCHEMBL23670239 | 0.76 | — | — | |
| SCHEMBL19285333 | 0.76 | — | — | |
| SCHEMBL23670238 | 0.76 | — | — | |
| SCHEMBL19285074 | 0.76 | — | — | |
| SCHEMBL30999483 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL13430541 | 0.76 | — | — | |
| SCHEMBL15850621 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108559-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASES THROUGH INHIBITION OF DNA METHYLATION AND HISTONE DEACETYLASE | SUPERGEN, INC. | 2008-05-08 | — | — | US | disclosed |
| US-20070254835-A1 | COMPOSITION AND METHOD FOR TREATING NEUROLOGICAL DISORDERS | SUPERGEN INC. | 2007-11-01 | — | — | US | disclosed |
| US-7276228-B2 | Methods for treating hematological disorders through inhibition of DNA methylation and histone deacetylase | SUPERGEN, INC. (US) | 2007-10-02 | — | — | US | disclosed |