Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395452 | 0.90 | KMT2A (0.52) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL2840268 | 0.81 | KMT2A (0.61) | KMT2AMEN1S1PR3CNR1CNR2 | |
| SCHEMBL2002973 | 0.80 | CYP1A2 (0.44) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8215475 | 0.78 | CES2 (0.52) | KMT2AMEN1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14790234 | 0.77 | KMT2A (0.56) | KMT2AMEN1S1PR3CNR1CNR2 | |
| SCHEMBL19118080 | 0.76 | HPGD (0.65) | KMT2ALMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL13204521 | 0.76 | HPGD (0.65) | KMT2ALMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL14868117 | 0.76 | KMT2A (0.48) | KMT2ALMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1692271 | 0.76 | HPGD (0.65) | KMT2ALMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL6691326 | 0.75 | KMT2A (0.56) | KMT2AMEN1S1PR3CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057856-A2 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1 AND/OR NF-KAPPAB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |