Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.91 |
| ▸ | PGR | P06401 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.91 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.91 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.91 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.91 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.91 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.91 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.91 |
| ▸ | PDE4A | P27815 | 1/20 | 0.91 |
| ▸ | UBE2M | P61081 | 1/20 | 0.91 |
| ▸ | NEDD8 | Q15843 | 1/20 | 0.91 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Micafungin SCHEMBL16550435 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL13575751 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14071559 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL19600986 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL1652133 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL23001458 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL37671 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14403608 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL14380016 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 | |
| Micafungin SCHEMBL31615511 | 0.95 | ESR1 (1.00) | ESR1PGRADORA3CHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375081-B2 | Therapeutic combination of a pneumocandin derivative and an antifungal agent | ASTELLAS PHARMA INC. (JP) | 2008-05-20 | — | — | US | disclosed |