Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366841 | 0.93 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28884841 | 0.93 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20564564 | 0.93 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20564938 | 0.93 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL20564903 | 0.92 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28371002 | 0.89 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28366896 | 0.89 | KMT2A (0.59) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL28372521 | 0.88 | KMT2A (0.55) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL27464177 | 0.87 | KMT2A (0.58) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL21470146 | 0.86 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368563-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-07-05 | — | — | US | disclosed |
| US-7235543-B2 | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof | SCHERING CORPORATION (US) | 2007-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155675-A1 | Substituted azetidinone compunds, processes for preparing the same, formulations and uses thereof | APOB, NPC1L1, CYP46A1 | KMT2A 2537/4885SMN1; SMN2 207/4885ALDH1A1 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.