Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600035 | 0.86 | SMN1; SMN2 (0.47) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL11330644 | 0.85 | RAB9A (0.59) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL10271315 | 0.84 | RAB9A (0.66) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL19941789 | 0.82 | RAB9A (0.61) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL15086785 | 0.82 | RAB9A (0.56) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL17038162 | 0.82 | RAB9A (0.56) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL20653568 | 0.82 | RAB9A (0.56) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL26426430 | 0.82 | RAB9A (0.56) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL20049378 | 0.81 | RAB9A (0.54) | RAB9AMAPTAPPNPC1GAA | |
| SCHEMBL23176734 | 0.79 | RAB9A (0.53) | RAB9AMAPTAPPNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008047883-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENES FOR TREATMENT OF MENTAL DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-24 | — | — | WO | disclosed |