SCHEMBL1421902

SCHEMBL1421902

O=C(ON1C(=O)CCC1=O)C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.41
CHRM4 P08173 2/20 0.41
CHRM1 P11229 2/20 0.41
CHRM3 P20309 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
KMT2A Q03164 2/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 4/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 3/20 0.36
GAA P10253 2/20 0.35
ELANE P08246 1/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
MIF P14174 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15492415 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL18685665 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL19404105 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL15247085 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL19880058 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL23424118 1.00 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL29572047 0.98 CHRM2 (0.40) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL9237508 0.98 SMN1; SMN2 (0.38) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL5339321 0.94 SMN1; SMN2 (0.42) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2
SCHEMBL17776136 0.90 MGLL (0.33) CHRM2CHRM4CHRM1CHRM3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119524119-A Nanoparticle vaccine for mucosal immunity and preparation method and application thereof 中国科学院过程工程研究所 2025-02-28 CN claimed
CN-118010978-A Preparation method of alkaline phosphatase-labeled human epididymal protein 4 antibody 桂林优利特医疗电子有限公司 2024-05-10 CN claimed
CN-109496149-B Formulation of antibodies and drug conjugates thereof 根马布股份公司 2022-10-14 CN claimed
CN-112285353-A Method for improving anti-biotin interference capability and sensitivity of chemiluminescence kit of streptavidin-biotin reaction system 武汉生之源生物科技股份有限公司 2021-01-29 CN claimed
CN-119053346-A Tissue-specific imaging and therapeutic agents targeting proteins expressed on muscle cell surfaces 建新公司 2024-11-29 CN disclosed
CN-118217402-A Combination therapy for C3 inhibition 阿佩利斯制药有限公司 2024-06-21 CN disclosed
CN-118010978-A Preparation method of alkaline phosphatase-labeled human epididymal protein 4 antibody 桂林优利特医疗电子有限公司 2024-05-10 CN disclosed
CN-117503905-A dosing regimen 阿佩利斯制药有限公司 2024-02-06 CN disclosed
CN-113156118-B Diagnostic marker and application thereof in diagnosis of COVID-19 and past infection detection of coronaviruses 上海交通大学 2024-01-12 CN disclosed
CN-116999396-A Modular compositions for removal of soluble biomolecules and related methods 纳米提克斯有限责任公司 2023-11-07 CN disclosed
CN-110882376-B Cell-reactive, long-acting or targeted compstatin analogs and related compositions and methods 阿佩利斯制药公司 2023-10-20 CN disclosed
CN-116617410-A AXL-specific antibody drug conjugates for cancer treatment 根马布股份公司 2023-08-22 CN disclosed
US-6800451-B2 MORE STABLE REACTION OF GLUCOSE WITH A BORONIC ACID COMPOUND SUCH AS 9,10-BISN-(BORONOBENZYL)-N-(3-(METHYACRYLAMIDO) PROPYLAMINO)METHYLANTHRACENE SENSORS FOR MEDICINE AND SCIENCE, INC. 2004-10-05 US disclosed
WO-2003078424-A1 DETECTION OF GLUCOSE IN SOLUTIONS ALSO CONTAINING AN ALPHA-HYDROXY ACID OR A BETA-DIKETONE SENSORS FOR MEDICINE AND SCIENCE, INC. (US) 2003-09-25 WO disclosed
US-20030082663-A1 Detection of glucose in solutions also containing an alpha-hydroxy acid or a beta-diketone SENSORS FOR MEDICINE AND SCIENCE, INC. 2003-05-01 US disclosed
US-6068962-A NOVOLAK RESIN AS AN ALKALI-SOLUBLE COMPONENT; QUINONEDIAZIDE; ACID GENERATOR; ANTHRACENE DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-30 US disclosed
CN-1208465-A Method of determining the hepatic status of an individual, including a liver transplant recipient BIOTRIN INTELLECTUAL PTY LTD (IE) 1999-02-17 CN disclosed
EP-0831371-A2 Positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-25 EP disclosed
WO-1990014103-A1 POLYPEPTIDE-ANTIBODY CONJUGATE FOR INHIBITING CELL ADHESION SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1990-11-29 WO disclosed
US-4401594-A PROTEOLYTIC ENZYME INHIBIJTORS; CARDIOVASCULAR AND MUSCULAR DISORDERS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-08-30 US disclosed