Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219296 | 0.95 | SIGMAR1 (0.35) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219564 | 0.92 | SIGMAR1 (0.39) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219547 | 0.91 | RARB (0.36) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219370 | 0.91 | RARB (0.36) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219996 | 0.89 | SIGMAR1 (0.41) | SIGMAR1ACP3RARBRARARARG | |
| SCHEMBL14219556 | 0.88 | SIGMAR1 (0.40) | SIGMAR1ACP3RARBRARARARG | |
| SCHEMBL14219366 | 0.85 | RARB (0.38) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219953 | 0.84 | SIGMAR1 (0.34) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219419 | 0.84 | SIGMAR1 (0.34) | SIGMAR1ACP3ESR1ESR2RARB | |
| SCHEMBL14219957 | 0.84 | ACP3 (0.34) | SIGMAR1ACP3ESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |