Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ABAT | P80404 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219594 | 1.00 | PDE5A (0.34) | PDE5ASLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL14220032 | 0.93 | PDE5A (0.32) | PDE5ASLC6A4IDO1FFAR1KDM1A | |
| SCHEMBL14219605 | 0.86 | IDO1 (0.34) | SLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL14219487 | 0.85 | FFAR4 (0.35) | IDO1SMN1; SMN2 | |
| SCHEMBL14219987 | 0.85 | SIGMAR1 (0.32) | PDE5A | |
| SCHEMBL14219592 | 0.84 | IDO1 (0.33) | SLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL14219333 | 0.84 | IDO1 (0.33) | SLC6A4SLC6A2SLC6A3IDO1 | |
| SCHEMBL14219603 | 0.83 | IDO1 (0.32) | SLC6A4SLC6A2SLC6A3IDO1ALDH1A1 | |
| SCHEMBL14219434 | 0.83 | SLC6A2 (0.31) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14219452 | 0.83 | SLC6A2 (0.31) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |