Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024893 | 0.87 | CYP3A4 (0.64) | HPGDALDH1A1CYP3A4CA2TDP1 | |
| SCHEMBL19024922 | 0.83 | CYP3A4 (0.67) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL25778290 | 0.82 | CYP3A4 (0.69) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL2719939 | 0.82 | HPGD (0.62) | HPGDALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL14219263 | 0.81 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL17616866 | 0.80 | CYP3A4 (0.66) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL17616871 | 0.79 | CYP3A4 (0.64) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL19024941 | 0.79 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2TDP1TSHR | |
| SCHEMBL3665504 | 0.79 | PPID (0.62) | HPGDALDH1A1TDP1LMNAHDAC3 | |
| SCHEMBL16345178 | 0.78 | CYP3A4 (0.62) | HPGDALDH1A1CYP3A4CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911438-A2 | Cosmetic composition containing a derivative of dibenzoylmethane and a arylalkyl amide or ester compound; method of photostabilising the derivative of dibenzoylmethane | L'Oréal (FR) | 2008-04-16 | — | — | EP | disclosed |
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | L'OREAL (FR) | 2008-01-24 | — | — | US | disclosed |
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | L'OREAL (FR) | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080019930-A1 | Dibenzoylmethane sunscreens photostabilized with arylalkyl amide or ester compounds | TYR, DDT, AADAC | HPGD 909/4885ALDH1A1 110/4885CYP3A4 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.