Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219299 | 1.00 | ACP3 (0.40) | ACP3ESR1ESR2AKR1C2AKR1C1 | |
| SCHEMBL14219365 | 0.95 | ACP3 (0.37) | ACP3ESR1ESR2AKR1C2AKR1C1 | |
| SCHEMBL14219361 | 0.91 | APP (0.38) | ACP3ESR1ESR2AKR1C2AKR1C1 | |
| SCHEMBL14219586 | 0.90 | SLC2A1 (0.38) | ACP3ESR1ESR2MDM2ADRB1 | |
| SCHEMBL14219291 | 0.85 | PPARG (0.39) | ACP3ESR1ESR2AKR1C2AKR1C1 | |
| SCHEMBL14219429 | 0.85 | CYP17A1 (0.44) | ACP3ESR1ESR2AKR1C2ADRB1 | |
| SCHEMBL14219899 | 0.83 | FFAR1 (0.42) | ACP3ESR1ESR2AKR1C2AKR1C1 | |
| SCHEMBL5165913 | 0.83 | ESR1 (0.43) | ACP3ESR1ESR2ADRB1ADRB3 | |
| SCHEMBL5165903 | 0.83 | ESR1 (0.43) | ACP3ESR1ESR2ADRB1ADRB3 | |
| SCHEMBL14219290 | 0.83 | ANPEP (0.39) | ACP3ESR1ESR2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |