Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219899 | 0.88 | FFAR1 (0.42) | PPARGPPARAFFAR1SLC6A4AKR1C2 | |
| SCHEMBL14219365 | 0.88 | ACP3 (0.37) | AKR1C2AKR1C1ACP3ESR1ESR2 | |
| SCHEMBL14219431 | 0.88 | PDPK1 (0.40) | PPARGAKR1C2ACP3ESR1ESR2 | |
| SCHEMBL14219565 | 0.86 | SIGMAR1 (0.40) | PPARGPPARAFFAR1SLC6A4AKR1C2 | |
| SCHEMBL14219896 | 0.86 | SIGMAR1 (0.40) | PPARGPPARAFFAR1SLC6A4AKR1C2 | |
| SCHEMBL14219290 | 0.85 | ANPEP (0.39) | SLC6A4ACP3ESR1ESR2ADRB1 | |
| SCHEMBL14219358 | 0.85 | ACP3 (0.40) | SLC6A4AKR1C2AKR1C1ACP3ESR1 | |
| SCHEMBL14219299 | 0.85 | ACP3 (0.40) | SLC6A4AKR1C2AKR1C1ACP3ESR1 | |
| SCHEMBL14219367 | 0.85 | CYP17A1 (0.42) | ACP3ESR1ESR2ADRB1ADRB3 | |
| SCHEMBL14219360 | 0.85 | CYP17A1 (0.42) | ACP3ESR1ESR2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |