Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 4/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219900 | 1.00 | TSHR (0.48) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL14219553 | 1.00 | TSHR (0.48) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL14219892 | 1.00 | TSHR (0.48) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL14219425 | 0.95 | GRIA1 (0.47) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL29065584 | 0.91 | ESR1 (0.47) | TSHRLSSCNR1CNR2MAOA | |
| SCHEMBL14219307 | 0.85 | TSHR (0.40) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL14219561 | 0.85 | TSHR (0.40) | TSHRHSD17B10MMP12MMP13GRIA1 | |
| SCHEMBL28848265 | 0.84 | MAOB (0.47) | TSHRGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29244942 | 0.82 | ESR1 (0.57) | TSHRHSD17B10GRIA1GRIA2GRIA3 | |
| SCHEMBL13558237 | 0.82 | ESR1 (0.57) | TSHRHSD17B10GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |