SCHEMBL28848265

SCHEMBL28848265

CC(Cc1ccccc1)c1ccc(C#N)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
MAOA P21397 6/20 0.46
TSHR P16473 1/20 0.45
GRIA1 P42261 1/20 0.43
GRIA2 P42262 1/20 0.43
GRIA3 P42263 1/20 0.43
GRIA4 P48058 1/20 0.43
FFAR1 O14842 1/20 0.42
CYP2A6 P11509 2/20 0.42
SLC6A2 P23975 2/20 0.42
TAAR1 Q96RJ0 2/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
ALOX5AP P20292 1/20 0.42
NISCH Q9Y2I1 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29065584 0.93 ESR1 (0.47) MAOBESR1ESR2MAOATSHR
SCHEMBL29244942 0.91 ESR1 (0.57) MAOBESR1ESR2TSHRGRIA1
SCHEMBL13558237 0.91 ESR1 (0.57) MAOBESR1ESR2TSHRGRIA1
SCHEMBL14219425 0.88 GRIA1 (0.47) MAOBESR1ESR2TSHRGRIA1
SCHEMBL29033902 0.88 CYP19A1 (0.45) MAOBESR1ESR2MAOAGRIA1
SCHEMBL14219376 0.84 TSHR (0.48) MAOBESR1ESR2MAOATSHR
SCHEMBL14219892 0.84 TSHR (0.48) MAOBESR1ESR2MAOATSHR
SCHEMBL14219553 0.84 TSHR (0.48) MAOBESR1ESR2MAOATSHR
SCHEMBL14219900 0.84 TSHR (0.48) MAOBESR1ESR2MAOATSHR
SCHEMBL3172156 0.81 HTR2A (0.51) ESR1ESR2CYP2A6SLC6A4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107004458-A Electrically conductive composition, technique and application 汉高股份有限及两合公司 2017-08-01 CN disclosed