Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219401 | 0.90 | ESR1 (0.36) | ESR1ESR2IDO1APPSLC18A3 | |
| SCHEMBL14219321 | 0.90 | ESR1 (0.36) | ESR1ESR2IDO1APPSLC18A3 | |
| SCHEMBL14219468 | 0.89 | PPARG (0.38) | ESR1ESR2MEN1KMT2ASLC6A2 | |
| SCHEMBL14220026 | 0.89 | PPARG (0.38) | ESR1ESR2MEN1KMT2ASLC6A2 | |
| SCHEMBL14220027 | 0.89 | ESR1 (0.36) | ESR1ESR2IDO1APPSLC18A3 | |
| SCHEMBL14219964 | 0.89 | MAOB (0.34) | SLC6A4SLC6A3MAOBCCR5 | |
| SCHEMBL14219479 | 0.89 | MAOB (0.34) | SLC6A4SLC6A3MAOBCCR5 | |
| SCHEMBL14219960 | 0.88 | GRM2 (0.34) | MEN1KMT2ASLC6A4SLC6A3IDO1 | |
| SCHEMBL14219941 | 0.88 | GRM2 (0.34) | MEN1KMT2ASLC6A4SLC6A3IDO1 | |
| SCHEMBL14219406 | 0.88 | ESR1 (0.41) | ESR1ESR2IDO1APPSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |