Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219479 | 1.00 | MAOB (0.34) | MAOBSIGMAR1SLC6A3HCRTR1HCRTR2 | |
| SCHEMBL14219960 | 0.93 | GRM2 (0.34) | MAOBSIGMAR1SLC6A3HCRTR1HCRTR2 | |
| SCHEMBL14219941 | 0.93 | GRM2 (0.34) | MAOBSIGMAR1SLC6A3HCRTR1HCRTR2 | |
| SCHEMBL14219596 | 0.89 | PPARG (0.33) | MAOBSLC6A3SLC6A4POLB | |
| SCHEMBL14219990 | 0.89 | PPARG (0.33) | MAOBSLC6A3SLC6A4POLB | |
| SCHEMBL14219392 | 0.89 | ESR1 (0.35) | MAOBSLC6A3SLC6A4CCR5 | |
| SCHEMBL14219988 | 0.88 | HCRTR1 (0.34) | MAOBSIGMAR1HCRTR1HCRTR2POLB | |
| SCHEMBL14219573 | 0.87 | BACE1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL14219571 | 0.87 | MAOB (0.32) | MAOBSIGMAR1POLB | |
| SCHEMBL14219946 | 0.87 | HAT1 (0.34) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650285-B1 | Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element | SEIMI CHEM KK (JP) | 2008-04-30 | — | — | EP | disclosed |