Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAP2K1 | Q02750 | 8/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.44 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219638 | 0.90 | MEN1 (0.58) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14223058 | 0.90 | MEN1 (0.60) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14220117 | 0.90 | MEN1 (0.51) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14222859 | 0.90 | MEN1 (0.58) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14219751 | 0.90 | MEN1 (0.60) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14219827 | 0.90 | MEN1 (0.60) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14219640 | 0.89 | MAP2K1 (0.56) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14219645 | 0.89 | MEN1 (0.58) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14223214 | 0.88 | MEN1 (0.55) | MEN1KMT2ATDP1MAP2K1RAF1 | |
| SCHEMBL14219832 | 0.87 | MEN1 (0.45) | MEN1KMT2ATDP1MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008041088-A2 | N-HYDROXY BENZAMIDES WITH ANTITUMOR ACTIVITY | EOS (ETHICAL ONCOLOGY SCIENCE) S.P.A. (IT) | 2008-04-10 | — | — | WO | disclosed |
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |