Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAP2K1 | Q02750 | 9/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.47 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.34 |
| ▸ | SMC2 | O95347 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14223217 | 0.91 | MEN1 (0.47) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219632 | 0.90 | MEN1 (0.62) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219640 | 0.86 | MAP2K1 (0.56) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14222513 | 0.85 | MAP2K1 (0.51) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219751 | 0.85 | MEN1 (0.60) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14220130 | 0.85 | ALDH1A1 (0.37) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219843 | 0.82 | MAP2K1 (0.45) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14223052 | 0.82 | MAP2K1 (0.45) | MAP2K1CSNK2A2MAP2K2SMC2EGFR | |
| SCHEMBL14222862 | 0.82 | RAF1 (0.46) | MEN1KMT2ATDP1MAP2K1CSNK2A2 | |
| SCHEMBL14219656 | 0.81 | PTGS2 (0.41) | MEN1KMT2ATDP1MAP2K1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |