Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.56 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219611 | 0.89 | MAP2K1 (0.62) | MAP2K1MAP2K2PIM1CAMK2BABCB11 | |
| SCHEMBL14219652 | 0.89 | MAP2K1 (0.43) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14220152 | 0.88 | MAP2K1 (0.63) | MAP2K1MAP2K2PIM1CAMK2BABCB11 | |
| SCHEMBL14219641 | 0.86 | MAP2K1 (0.54) | MAP2K1MAP2K2PIM1CAMK2BMAPK1 | |
| SCHEMBL14219653 | 0.82 | MAP2K1 (0.60) | MAP2K1MAP2K2PIM1CAMK2BABCB11 | |
| SCHEMBL4596340 | 0.81 | MAP2K1 (0.64) | MAP2K1MAP2K2PIM1CAMK2BCYP2C9 | |
| SCHEMBL14220178 | 0.79 | MAP2K1 (0.41) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14220160 | 0.79 | MAP2K1 (0.49) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14220150 | 0.79 | MAP2K1 (0.48) | MAP2K1MAP2K2PIM1CAMK2BHDAC3 | |
| SCHEMBL14223208 | 0.79 | MEN1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |