Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 20/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | SMC2 | O95347 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.40 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219849 | 0.90 | MAP2K1 (0.43) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14220120 | 0.90 | MAP2K1 (0.36) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14220123 | 0.88 | MEN1 (0.35) | MAP2K1MAP2K2ABCB11NQO2 | |
| SCHEMBL14219698 | 0.88 | MAP2K1 (0.45) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14223050 | 0.84 | MAP2K1 (0.44) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14219652 | 0.84 | MAP2K1 (0.43) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14220172 | 0.81 | DHODH (0.35) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14219629 | 0.81 | MAP2K1 (0.45) | MAP2K1MAP2K2ABCB11NQO2SMC2 | |
| SCHEMBL14219684 | 0.81 | LMNA (0.42) | — | |
| SCHEMBL14220176 | 0.80 | MAP2K1 (0.47) | MAP2K1MAP2K2ABCB11NQO2SMC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |