Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219524 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL14219590 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5793487 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5793486 | 1.00 | LMNA (0.46) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5792863 | 0.98 | SMN1; SMN2 (0.44) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL5790310 | 0.98 | SMN1; SMN2 (0.44) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8956038 | 0.94 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL17042699 | 0.94 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8956065 | 0.94 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8956165 | 0.94 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343861-B1 | BRANCHED PRIMARY ALCOHOL COMPOSITIONS AND DERIVATIVES THEREOF | SHELL INT RESEARCH (NL) | 2008-04-16 | — | — | EP | disclosed |