SCHEMBL14219958

SCHEMBL14219958

CCOc1ccc(CCC2CCC(c3ccc(C[C@H](C)c4ccccc4)cc3)CC2)cc1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.38
PTGDR2 Q9Y5Y4 3/20 0.34
HCRTR1 O43613 2/20 0.33
HCRTR2 O43614 2/20 0.33
FAAH O00519 1/20 0.33
CCR5 P51681 3/20 0.33
FFAR4 Q5NUL3 1/20 0.32
POLB P06746 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14219927 1.00 KDM1A (0.38) KDM1APTGDR2HCRTR1HCRTR2FAAH
SCHEMBL14219600 0.94 KDM1A (0.40) KDM1APTGDR2FAAHCCR5FFAR4
SCHEMBL14219984 0.94 KDM1A (0.40) KDM1APTGDR2FAAHCCR5FFAR4
SCHEMBL14219959 0.90 FFAR4 (0.36) PTGDR2HCRTR1HCRTR2FFAR4
SCHEMBL14219925 0.90 FFAR4 (0.36) PTGDR2HCRTR1HCRTR2FFAR4
SCHEMBL14219391 0.89 KDM1A (0.45) KDM1APTGDR2FAAHCCR5POLB
SCHEMBL14219912 0.89 KDM1A (0.45) KDM1APTGDR2FAAHCCR5POLB
SCHEMBL14219926 0.87 HCRTR1 (0.38) KDM1AHCRTR1HCRTR2CCR5
SCHEMBL14219956 0.87 HCRTR1 (0.38) KDM1AHCRTR1HCRTR2CCR5
SCHEMBL14219486 0.86 KDM1A (0.39) KDM1APTGDR2FAAHCCR5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650285-B1 Liquid crystal composition containing an optically active compound and liquid crystal electro-optical element SEIMI CHEM KK (JP) 2008-04-30 EP disclosed