Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 15/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14219716 | 0.90 | ALDH1A1 (0.36) | MEN1KMT2ATDP1ALDH1A1DHODH | |
| SCHEMBL14220171 | 0.89 | MEN1 (0.41) | MEN1KMT2ATDP1DHODHMAP2K1 | |
| SCHEMBL14222856 | 0.88 | MEN1 (0.40) | MEN1KMT2ATDP1ALDH1A1DHODH | |
| SCHEMBL14220157 | 0.86 | MEN1 (0.42) | MEN1KMT2ATDP1ALDH1A1MAP2K1 | |
| SCHEMBL14219638 | 0.85 | MEN1 (0.58) | MEN1KMT2ATDP1DHODHMAP2K1 | |
| SCHEMBL14220111 | 0.85 | ALDH1A1 (0.40) | MEN1KMT2ATDP1ALDH1A1DHODH | |
| SCHEMBL14222863 | 0.84 | MAP2K1 (0.47) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL14220170 | 0.84 | MAP2K1 (0.47) | MEN1KMT2ATDP1MAP2K1MAP2K2 | |
| SCHEMBL14219826 | 0.83 | TDP1 (0.36) | MEN1KMT2ATDP1DHODHMAP2K1 | |
| SCHEMBL14219644 | 0.82 | MEN1 (0.42) | MEN1KMT2ATDP1ALDH1A1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |