Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.66 |
| ▸ | POLB | P06746 | 6/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651165 | 0.85 | MAPK1 (0.60) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL4137558 | 0.85 | MAPK1 (0.60) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL4137556 | 0.85 | MAPK1 (0.60) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5459723 | 0.78 | MEN1 (0.87) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5459720 | 0.78 | MEN1 (0.87) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL14220547 | 0.78 | PTPN1 (0.74) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5457241 | 0.75 | PTPN1 (0.72) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5457238 | 0.75 | PTPN1 (0.72) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5457187 | 0.74 | MEN1 (0.76) | MEN1KMT2APOLBGAACASP3 | |
| SCHEMBL5457193 | 0.74 | MEN1 (0.76) | MEN1KMT2APOLBGAACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1916249-A1 | 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents | LEK Pharmaceuticals D.D. (SI) | 2008-04-30 | — | — | EP | disclosed |