Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 10/20 | 0.73 |
| ▸ | KCNAB1 | Q14722 | 10/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945192 | 0.89 | KCNA1 (0.92) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1947206 | 0.85 | KCNA1 (1.00) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1945507 | 0.84 | KCNA1 (1.00) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1945902 | 0.83 | KCNA1 (0.82) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1945846 | 0.82 | KCNA1 (1.00) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1945005 | 0.81 | KCNA1 (0.92) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1946654 | 0.81 | KCNA1 (0.84) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12540053 | 0.80 | KCNA1 (0.77) | KCNA1KCNAB1MEN1KMT2ATP53 | |
| SCHEMBL1946349 | 0.80 | KCNA1 (0.83) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL1946194 | 0.76 | KCNA1 (0.84) | KCNA1KCNAB1ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008038053-A1 | ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-04-03 | — | — | WO | disclosed |