Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | FLT4 | P35916 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253558 | 0.90 | SMN1; SMN2 (0.36) | MAPTKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL2158238 | 0.84 | MAPT (0.50) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL4157913 | 0.82 | FLT1 (0.39) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL1961039 | 0.82 | FLT1 (0.39) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL2158331 | 0.79 | TSHR (0.39) | KDM4EALDH1A1CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL14043169 | 0.78 | MAPT (0.44) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL4159892 | 0.78 | MAPT (0.45) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL4147674 | 0.77 | MAPT (0.42) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL1958399 | 0.76 | FLT1 (0.35) | RAB9AMAPTNPC1KDM4ECASP3 | |
| SCHEMBL4732198 | 0.75 | MAPT (0.48) | RAB9AMAPTNPC1KDM4ECASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008043791-A2 | THIOPHENE DERIVATIVES FOR TREATING HEPATITIS C | SMITHKLINE BEECHAM CORPORATION (US) | 2008-04-17 | — | — | WO | disclosed |