⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388645 | 0.81 | — | — | |
| SCHEMBL12793099 | 0.81 | — | — | |
| SCHEMBL270455 | 0.75 | TSHR (0.31) | — | |
| SCHEMBL1665615 | 0.71 | — | — | |
| SCHEMBL13467623 | 0.71 | — | — | |
| SCHEMBL6528151 | 0.69 | — | — | |
| SCHEMBL2003538 | 0.69 | HIF1A (0.33) | — | |
| SCHEMBL5134464 | 0.67 | — | — | |
| SCHEMBL16927545 | 0.67 | — | — | |
| SCHEMBL24933936 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365091-B2 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of PHEX | ENOBIA PHARMA (CA) | 2008-04-29 | — | — | US | disclosed |