SCHEMBL2003538

SCHEMBL2003538

O=CCCC(C=O)CC=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694699 0.85 HIF1A (0.39) HIF1ATSHRSMN1; SMN2ALDH1A1
SCHEMBL12793099 0.78
SCHEMBL20393985 0.76 HIF1A (0.45) HIF1ATSHRSMN1; SMN2
SCHEMBL5134464 0.76
SCHEMBL10970063 0.76
SCHEMBL9311922 0.74 AKR1B1 (0.31) HIF1ATSHRSMN1; SMN2
SCHEMBL28140181 0.74 ALDH1A1 (0.46) HIF1ATSHRSMN1; SMN2ALDH1A1
SCHEMBL270455 0.73 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL28275056 0.72 TSHR (0.67) TSHRSMN1; SMN2ALDH1A1
SCHEMBL6544702 0.72 ALDH1A1 (0.38) TSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964586-B2 by solid phase extraction from pregnant mares urine; contacting the urine with polymeric adsorption resins sufficient to adsorb the estrogen derivatives in the urine, then separating the resulting resin loaded with the mixture, washing and eluting the derivatives ABBOTT PRODUCTS GMBH (DE) 2011-06-21 US disclosed
EP-0980363-B9 PREPARATION OF ISOFLAVONES FROM LEGUMES NOVOGEN INC (US) 2010-09-01 EP disclosed
EP-0980363-B1 PREPARATION OF ISOFLAVONES FROM LEGUMES NOVOGEN INC (US) 2010-03-10 EP disclosed
EP-0980363-A4 PREPARATION OF ISOFLAVONES FROM LEGUMES NOVOGEN INC (US) 2008-11-19 EP disclosed
EP-1648916-B1 METHOD FOR OBTAINING A NATURAL MIXTURE OF CONJUGATED EQUINE ESTROGENS SOLVAY PHARM GMBH (DE) 2008-10-08 EP disclosed
EP-1648916-A1 METHOD FOR OBTAINING A NATURAL MIXTURE OF CONJUGATED EQUINE ESTROGENS Solvay Pharmaceuticals GmbH (DE) 2006-04-26 EP disclosed
US-7033621-B1 Isoflavone compositions produced from legumes NOVOGEN, INC. (US) 2006-04-25 US disclosed
CN-1214020-C Preparation of isoflavones from legumes NOVOGEN INC (US) 2005-08-10 CN disclosed
US-20050032767-A1 Method for obtaining a natural mixture of conjugated equine estrogens SOLVAY PHARMACEUTICALS GMBH (DE) 2005-02-10 US disclosed
WO-2005010021-A1 METHOD FOR OBTAINING A NATURAL MIXTURE OF CONJUGATED EQUINE ESTROGENS SOLVAY PHARMACEUTICALS GMBH (DE) 2005-02-03 WO disclosed
EP-0854388-B1 Negative-type image recording materials FUJI PHOTO FILM CO LTD (JP) 2003-08-13 EP disclosed
US-6146668-A CONTACTING PLANT MATERIAL WITH WATER, AN ENZYME WHICH CLEAVES ISOFLAVONE GLYCOSIDES TO AGLUCONE FORM AND ORGANIC SOLVENT, INCUBATING TO ALLOW ISOFLAVONES OF THE AGLUCONE FORM TO PARTITION INTO THE ORGANIC SOLVENT, RECOVERING ISOFLAVONES NOVOGEN, INC. (US) 2000-11-14 US disclosed
CN-1259130-A Preparation of isoflavones from leguminous plants NOVOGEN INC (US) 2000-07-05 CN disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0980363-A1 PREPARATION OF ISOFLAVONES FROM LEGUMES Novogen Inc. (US) 2000-02-23 EP disclosed
WO-1998049153-A1 PREPARATION OF ISOFLAVONES FROM LEGUMES NOVOGEN INC. (US) 1998-11-05 WO disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 EP disclosed